IGFBP3 antibody

• Background:

  IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.

• Synonyms:

  Insulin-like growth factor-binding protein 3 (IBP-3, IGF-binding protein 3, IGFBP-3) |IGFBP3|IBP3

• Gene ID:

  3486

• UniProt:

  P17936

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Insulin-like growth factor binding protein 3

• Target:

  IGFBP3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Signal Transduction, Cardiovascular, Immunology, Cancer, Stem Cells

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:500; IHC: 1:20-1:200; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  32 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF