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IDS antibody

CAT: 0710-FNab04130Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04130Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181) .
Synonyms
Iduronate 2-sulfatase|Alpha-L-iduronate sulfate sulfatase (Idursulfase) |Iduronate 2-sulfatase 42 kDa chain|Iduronate 2-sulfatase 14 kDa chain|IDS|SIDS
Gene ID
3423
UniProt
P22304
Host
Mouse
Reactivity
Human
Immunogen
Iduronate 2-sulfatase
Target
IDS
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
76 kDa, 55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2D2
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
1-300aa

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