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HNRNPU antibody

CAT: 0710-FNab03958Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03958Size:100 µg
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Background
Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double-and single-stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity) .
Synonyms
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) |GRIP120|Nuclear p120 ribonucleoprotein|Scaffold-attachment factor A (SAF-A) |p120|pp120|HNRNPU|C1orf199|HNRPU|SAFA|U21.1
Gene ID
3192
UniProt
Q00839
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Target
HNRNPU
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

UniProtKB · Q00839

Heterogeneous nuclear ribonucleoprotein U

HNRPU_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q00839
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HNRNPU
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hnRNP U
EC number
—
Processing
—
Secondary accessions
O75507, Q8N174, Q96HY9, Q9BQ09
Protein keywords

PTM

AcetylationADP-ribosylationCitrullinationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorChromatin regulatorDevelopmental proteinDNA-bindingRepressorRibonucleoproteinRNA-binding

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Biological rhythmsCell cycleCell divisionDifferentiationHost-virus interactionMitosismRNA processingmRNA splicingTranscriptionTranscription regulation

Cellular component

CentromereChromosomeCytoplasmCytoskeletonKinetochoreNucleusSpliceosome

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variantEpilepsy

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