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HLTF antibody

CAT: 0710-FNab03915Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03915Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity) . These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Synonyms
Helicase-like transcription factor|DNA-binding protein/plasminogen activator inhibitor 1 regulator|HIP116|RING finger protein 80|RING-type E3 ubiquitin transferase HLTF|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3|Sucrose nonfermenting protein 2-like 3|HLTF|HIP116A|RNF80|SMARCA3|SNF2L3|ZBU1
Gene ID
6596
UniProt
Q14527
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Helicase-like transcription factor
Target
HLTF
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
114 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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