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H1-6 antibody

CAT: 0710-FNab03875Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03875Size:100 µg
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Background
Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes (PubMed:26757249) . Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination (PubMed:26757249) . Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration (Probable) .
Synonyms
Histone H1t|Testicular H1 histone|H1-6|H1FT|H1T|HIST1H1T
Gene ID
3010
UniProt
P22492
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Histone cluster 1, H1t
Target
H1-6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P22492

Histone H1t

H1T_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22492
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
H1-6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6ISI1, Q8IUE8
Protein keywords

PTM

AcetylationCitrullinationPhosphoprotein

Cellular component

ChromosomeNucleus

Molecular function

Developmental proteinDNA-binding

Biological process

DifferentiationSpermatogenesis

Technical term

Proteomics identificationReference proteome

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