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GZMM antibody

CAT: 0710-FNab03738Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03738Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Synonyms
Granzyme M|Met-1 serine protease (Hu-Met-1) |Met-ase|Natural killer cell granular protease|GZMM|MET1
Gene ID
3004
UniProt
P51124
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Granzyme M (lymphocyte met-ase 1)
Target
GZMM
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P51124

Granzyme M

GRAM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51124
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GZMM
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.-
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

ApoptosisCytolysisImmunityInnate immunity

PTM

Disulfide bondGlycoproteinZymogen

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

Domain

Signal

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