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GRK6 antibody

CAT: 0710-FNab03656Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03656Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity) . Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro) .
Synonyms
G protein-coupled receptor kinase 6|G protein-coupled receptor kinase GRK6|GRK6|GPRK6
Gene ID
2870
UniProt
P43250
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
G protein-coupled receptor kinase 6
Target
GRK6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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