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GRIA4 antibody

CAT: 0710-FNab03646Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03646Size:100 µg
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Background
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Synonyms
Glutamate receptor 4 (GluR-4, GluR4) |AMPA-selective glutamate receptor 4|GluR-D|Glutamate receptor ionotropic, AMPA 4 (GluA4) |GRIA4|GLUR4
Gene ID
2893
UniProt
P48058
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Glutamate receptor, ionotrophic, AMPA 4
Target
GRIA4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
101 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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