GNAI3 antibody

• Background :

  Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.

• Synonyms :

  Guanine nucleotide-binding protein G (i) subunit alpha-3|G (i) alpha-3|GNAI3

• Gene ID :

  2773

• UniProt :

  P08754

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

• Target :

  GNAI3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:1000 - 1:2000; IHC: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  41 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC