Products for Research Use Only

GCK antibody

CAT: 0710-FNab03384Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03384Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Synonyms
Hexokinase-4 (HK4) |Glucokinase|Hexokinase type IV (HK IV) |Hexokinase-D|GCK
Gene ID
2645
UniProt
P35557
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Glucokinase (hexokinase 4)
Target
GCK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-52 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB