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GATC antibody

CAT: 0710-FNab03367Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03367Size:100 µg
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Background
Allows the formation of correctly charged Gln-tRNA (Gln) through the transamidation of misacylated Glu-tRNA (Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA (Gln) .
Synonyms
Glutamyl-tRNA (Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) |Protein 15E1.2|GATC|15E1.2
Gene ID
283459
UniProt
O43716
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Glutamyl-tRNA (Gln) amidotransferase, subunit C homolog (bacterial)
Target
GATC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
15 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IP

UniProtKB · O43716

Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

GATC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43716
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GATC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Glu-AdT subunit C, hGatC
EC number
—
Processing
Precursor
Secondary accessions
B3KSU7, Q3B824, Q3KNR8
Protein keywords

Disease

Disease variantPrimary mitochondrial disease

Cellular component

Mitochondrion

Biological process

Protein biosynthesis

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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