GALC antibody

• Background :

  This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Synonyms :

  Galactocerebrosidase (GALCERase) |Galactocerebroside beta-galactosidase|Galactosylceramidase|Galactosylceramide beta-galactosidase|GALC

• Gene ID :

  2581

• UniProt :

  P54803

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Galactosylceramidase

• Target :

  GALC

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  77 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC

• Immunogen Sequence :

  40-300aa