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FERMT3 antibody

CAT: 0710-FNab03078Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03078Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933) . Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity) . Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460) . Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity) . Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
Synonyms
Fermitin family homolog 3|Kindlin-3|MIG2-like protein|Unc-112-related protein 2|FERMT3|KIND3|MIG2B|URP2
Gene ID
83706
UniProt
Q86UX7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Fermitin family homolog 3 (Drosophila)
Target
FERMT3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
72-76 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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