FERMT1 antibody

• Background:

  Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

• Synonyms:

  Fermitin family homolog 1|Kindlerin|Kindlin syndrome protein|Kindlin-1|Unc-112-related protein 1|FERMT1|C20orf42|KIND1|URP1

• Gene ID:

  55612

• UniProt:

  Q9BQL6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Fermitin family homolog 1 (Drosophila)

• Target:

  FERMT1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Signal Transduction, Immunology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  70-77 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF