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EYA4 antibody

CAT: 0710-FNab02916Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02916Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) . 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity) .
Synonyms
Eyes absent homolog 4|EYA4
Gene ID
2070
UniProt
O95677
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Eyes absent homolog 4 (Drosophila)
Target
EYA4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Neuroscience, Cardiovascular, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
67 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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