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EPRS1 antibody

CAT: 0710-FNab02817Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02817Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
Synonyms
Bifunctional glutamate/proline--tRNA ligase|Bifunctional aminoacyl-tRNA synthetase|Cell proliferation-inducing gene 32 protein|Glutamatyl-prolyl-tRNA synthetase|EPRS1|EPRS|GLNS|PARS|QARS|QPRS
Gene ID
2058
UniProt
P07814
Host
Rabbit
Reactivity
Human
Immunogen
Glutamyl-prolyl-tRNA synthetase
Target
EPRS1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
171 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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