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ELAC2 antibody

CAT: 0710-FNab02732Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02732Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
Zinc phosphodiesterase ELAC protein 2|ElaC homolog protein 2|Heredity prostate cancer protein 2|Ribonuclease Z 2 (RNase Z 2) |tRNA 3 endonuclease 2|tRNase Z 2|ELAC2|HPC2
Gene ID
60528
UniProt
Q9BQ52
Host
Rabbit
Reactivity
Human
Immunogen
ElaC homolog 2 (E. coli)
Target
ELAC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
17-198aa

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