DYNC1LI1 antibody

CAT: 0710-FNab02585Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02585Size:100 µg
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Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Synonyms
Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) |Dynein light chain A (DLC-A) |Dynein light intermediate chain 1, cytosolic (DLIC-1) |DYNC1LI1|DNCLI1
Gene ID
51143
UniProt
Q9Y6G9
Host
Rabbit
Reactivity
Human
Immunogen
Dynein, cytoplasmic 1, light intermediate chain 1
Target
DYNC1LI1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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