DYNC1I2 antibody

• Background :

  Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.

• Synonyms :

  Cytoplasmic dynein 1 intermediate chain 2|Cytoplasmic dynein intermediate chain 2|Dynein intermediate chain 2, cytosolic (DH IC-2) |DYNC1I2|DNCI2|DNCIC2

• Gene ID :

  1781

• UniProt :

  Q13409

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Dynein, cytoplasmic 1, intermediate chain 2

• Target :

  DYNC1I2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  68 kDa and 72 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF