DTX4 antibody

• Background:

  Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity) . Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

• Synonyms:

  E3 ubiquitin-protein ligase DTX4|Protein deltex-4 (Deltex4) |RING finger protein 155|RING-type E3 ubiquitin transferase DTX4|DTX4|KIAA0937|RNF155

• Gene ID:

  23220

• UniProt:

  Q9Y2E6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Deltex homolog 4 (Drosophila)

• Target:

  DTX4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Signal Transduction, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  67-70 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF