DTX4 antibody

• Background :

  Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity) . Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

• Synonyms :

  E3 ubiquitin-protein ligase DTX4|Protein deltex-4 (Deltex4) |RING finger protein 155|RING-type E3 ubiquitin transferase DTX4|DTX4|KIAA0937|RNF155

• Gene ID :

  23220

• UniProt :

  Q9Y2E6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Deltex homolog 4 (Drosophila)

• Target :

  DTX4

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF

• Field of Research :

  Signal Transduction, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  67-70 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF