DTX3 antibody

• Background :

  Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity) . Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

• Synonyms :

  Probable E3 ubiquitin-protein ligase DTX3|Protein deltex-3 (Deltex3) |RING finger protein 154|RING-type E3 ubiquitin transferase DTX3|DTX3|RNF154

• Gene ID :

  196403

• UniProt :

  Q8N9I9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Deltex homolog 3

• Target :

  DTX3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Signal Transduction, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:1000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  38 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC