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DNAJA1 antibody

CAT: 0710-FNab02439Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02439Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Co-chaperone for HSPA8/Hsc70 (PubMed:10816573) . Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877) . Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510) . Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202) .
Synonyms
DnaJ homolog subfamily A member 1|DnaJ protein homolog 2|HSDJ|Heat shock 40 kDa protein 4|Heat shock protein J2 (HSJ-2) |Human DnaJ protein 2 (hDj-2) |DNAJA1|DNAJ2|HDJ2|HSJ2|HSPF4
Gene ID
3301
UniProt
P31689
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
DnaJ (Hsp40) homolog, subfamily A, member 1
Target
DNAJA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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