DNAJA1 antibody

• Background :

  Co-chaperone for HSPA8/Hsc70 (PubMed:10816573) . Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877) . Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510) . Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202) .

• Synonyms :

  DnaJ homolog subfamily A member 1|DnaJ protein homolog 2|HSDJ|Heat shock 40 kDa protein 4|Heat shock protein J2 (HSJ-2) |Human DnaJ protein 2 (hDj-2) |DNAJA1|DNAJ2|HDJ2|HSJ2|HSPF4

• Gene ID :

  3301

• UniProt :

  P31689

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  DnaJ (Hsp40) homolog, subfamily A, member 1

• Target :

  DNAJA1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:1000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  45 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC