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DLL4 antibody

CAT: 0710-FNab02416Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02416Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954) . Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313) . Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity) . During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344) .
Synonyms
Delta-like protein 4|Drosophila Delta homolog 4 (Delta4) |DLL4
Gene ID
54567
UniProt
Q9NR61
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Delta-like 4 (Drosophila)
Target
DLL4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Stem Cells, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
75-80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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