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DKC1 antibody

CAT: 0710-FNab02400Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02400Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs) . This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Synonyms
H/ACA ribonucleoprotein complex subunit DKC1|CBF5 homolog|Dyskerin|Nopp140-associated protein of 57 kDa|Nucleolar protein NAP57|Nucleolar protein family A member 4|snoRNP protein DKC1|DKC1|NOLA4
Gene ID
1736
UniProt
O60832
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Dyskeratosis congenita 1, dyskerin
Target
DKC1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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MBS9607322-01DKC1 Antibody

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