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DHRS4 antibody

CAT: 0710-FNab02373Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02373Size:100 µg
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Background
Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity) .
Synonyms
Dehydrogenase/reductase SDR family member 4|NADPH-dependent carbonyl reductase (CR) |NADPH-dependent retinol dehydrogenase/reductase (NRDR, humNRDR) |Peroxisomal short-chain alcohol dehydrogenase (PSCD) |SCAD-SRL|Short chain dehydrogenase/reductase family 25C member 2 (Protein SDR25C2) |Short-chain dehydrogenase/reductase family member 4|DHRS4|SDR25C2
Gene ID
10901
UniProt
Q9BTZ2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Dehydrogenase/reductase (SDR family) member 4
Target
DHRS4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q9BTZ2

Dehydrogenase/reductase SDR family member 4

DHRS4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BTZ2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DHRS4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.1.1.184
Processing
—
Secondary accessions
B2RB10, B7WNS9, D3YTB8, E2QRL8, O95162, Q20CR0, Q2LC19, Q2LE81, Q58IU4, Q6E0Y1, Q6UWU3, Q71UQ6, Q8TD03, Q9H3N5, Q9NV08
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

NADP

Cellular component

NucleusPeroxisome

Molecular function

Oxidoreductase

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