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DHRS2 antibody

CAT: 0710-FNab02371Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02371Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Synonyms
Dehydrogenase/reductase SDR family member 2, mitochondrial|Dicarbonyl reductase HEP27|Protein D|Short chain dehydrogenase/reductase family 25C member 1 (Protein SDR25C1) |DHRS2|SDR25C1
Gene ID
10202
UniProt
Q13268
Host
Rabbit
Reactivity
Human
Immunogen
Dehydrogenase/reductase (SDR family) member 2
Target
DHRS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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