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DGKQ antibody

CAT: 0710-FNab02361Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02361Size:100 µg
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Background
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA) . May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity) . May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
Synonyms
Diacylglycerol kinase theta (DAG kinase theta, DGKtheta) |Diglyceride kinase theta (DGK-theta) |DGKQ|DAGK4
Gene ID
1609
UniProt
P52824
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Diacylglycerol kinase, theta 110kDa
Target
DGKQ
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P52824

Diacylglycerol kinase theta

DGKQ_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52824
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DGKQ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DAG kinase theta, DGKtheta
EC number
2.7.1.107, 2.7.1.93
Processing
—
Secondary accessions
Q6P3W4
Protein keywords

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Cellular component

Cell membraneCytoplasmCytoskeletonMembraneNucleusSynapse

Molecular function

KinaseTransferase

Biological process

Lipid metabolism

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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