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DDRGK1 antibody

CAT: 0710-FNab02292Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02292Size:100 µg
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Background
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription (PubMed:25219498) . May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B (PubMed:23675531) . May also play a role in the cellular response to endoplasmic reticulum stress (By similarity) .
Synonyms
DDRGK domain-containing protein 1|Dashurin|UFM1-binding and PCI domain-containing protein 1|DDRGK1|C20orf116|UFBP1
Gene ID
65992
UniProt
Q96HY6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
DDRGK domain containing 1
Target
DDRGK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36-46 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · Q96HY6

DDRGK domain-containing protein 1

DDRGK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96HY6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DDRGK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NIU5, C9JSZ5, Q9BW47
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Dwarfism

Cellular component

Endoplasmic reticulumMembrane

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Domain

TransmembraneTransmembrane helix

Biological process

Ubl conjugation pathway

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