Products for Research Use Only
RegisterLogin

CYP4F11 antibody

CAT: 0710-FNab02170Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab02170Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531) . Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081) . Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545) .
Synonyms
Cytochrome P450 4F11 (CYPIVF11) |3-hydroxy fatty acids omega-hydroxylase CYP4F11|Docosahexaenoic acid omega-hydroxylase|Long-chain fatty acid omega-monooxygenase|Phylloquinone omega-hydroxylase CYP4F11|CYP4F11
Gene ID
57834
UniProt
Q9HBI6
Host
Rabbit
Reactivity
Human
Immunogen
Cytochrome P450, family 4, subfamily F, polypeptide 11
Target
CYP4F11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q9HBI6

Cytochrome P450 4F11

CP4FB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HBI6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP4F11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CYPIVF11
EC number
1.14.14.1
Processing
—
Secondary accessions
A0A024R7G0, A8K059, O75254, Q96AQ5
Protein keywords

Cellular component

Endoplasmic reticulumMembraneMicrosome

Biological process

Fatty acid metabolismLipid metabolism

Ligand

HemeIronMetal-bindingNADP

Molecular function

MonooxygenaseOxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
FNab02171CYP4F11-Specific antibody
P9484-01Recombinant Human CYP4F11
FNab02168CYP4A11 antibody
FNab02172CYP4F12 antibody
FNab02167CYP46A1 antibody
FNab02169CYP4B1 antibody
FNab02160CYP2F1 antibody
FNab02173CYP4F3 antibody
FNab02174CYP4F8 antibody
FNab02175CYP4Z1-Specific antibody

Alternative Products

CatalogName
70R-16721CYP4F11 antibody

Popular Products