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CTDSP2 antibody

CAT: 0710-FNab02051Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02051Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Synonyms
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2|Nuclear LIM interactor-interacting factor 2 (NLI-interacting factor 2) |Protein OS-4|Small C-terminal domain phosphatase 2|Small CTD phosphatase 2 (SCP2) |CTDSP2|NIF2|OS4|SCP2
Gene ID
10106
UniProt
O14595
Host
Rabbit
Reactivity
Human
Immunogen
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Target
CTDSP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
31 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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