CTDSP1 antibody

• Background :

  Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

• Synonyms :

  Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1|Nuclear LIM interactor-interacting factor 3 (NLI-IF, NLI-interacting factor 3) |Small C-terminal domain phosphatase 1 (SCP1, Small CTD phosphatase 1) |CTDSP1|NIF3|NLIIF|SCP1

• Gene ID :

  58190

• UniProt :

  Q9GZU7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

• Target :

  CTDSP1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  33 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB