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CSNK1A1 antibody

CAT: 0710-FNab02020Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02020Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108) . May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688) .
Synonyms
Casein kinase I isoform alpha (CKI-alpha) |CK1|CSNK1A1
Gene ID
1452
UniProt
P48729
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Casein kinase 1, alpha 1
Target
CSNK1A1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cell Division and Proliferation, Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42-45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

UniProtKB · P48729

Casein kinase I isoform alpha

KC1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48729
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CSNK1A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CKI-alpha
EC number
2.7.11.1
Processing
—
Secondary accessions
D3DQG0, D3DQG1, Q4JJA0, Q5U046, Q5U047, Q6FGA2, Q71TU5, Q96HD2, Q9UDK3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell divisionMitosisWnt signaling pathway

Cellular component

Cell projectionCentromereChromosomeCytoplasmCytoskeletonKinetochoreNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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