CLEC4M antibody

• Background :

  Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus (PubMed:12050398, PubMed:12502850) . Acts as an attachment receptor for hepatitis C virus (PubMed:15371595, PubMed:16816373) . Acts as an attachment receptor for HIV-1 (PubMed:21277928, PubMed:12502850) . Acts as an attachment receptor for human coronavirus 229E (PubMed:17037540) . Acts as an attachment receptor for human cytomegalovirus/HHV-5 (PubMed:12433371) . Acts as an attachment receptor for influenzavirus (PubMed:21191006) . Acts as an attachment receptor for SARS coronavirus (PubMed:15479853) . Acts as an attachment receptor for west-nile virus (PubMed:16415006) . Acts as an attachment receptor for Japanese encephalitis virus (PubMed:24623090) . Acts as an attachment receptor for Marburg virus glycoprotein (PubMed:15479853) . Recognition of M.bovis by dendritic cells may occur partially via this molecule (PubMed:21203928) .

• Synonyms :

  C-type lectin domain family 4 member M|CD209 antigen-like protein 1|DC-SIGN-related protein (DC-SIGNR) |Dendritic cell-specific ICAM-3-grabbing non-integrin 2 (DC-SIGN2) |Liver/lymph node-specific ICAM-3-grabbing non-integrin (L-SIGN) |CLEC4M|CD209L|CD209L1|CD299

• Gene ID :

  10332

• UniProt :

  Q9H2X3

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  C-type lectin domain family 4, member M

• Target :

  CLEC4M

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, WB

• Field of Research :

  Immunology, Cardiovascular, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, WB