CLEC4C antibody

• Background:

  Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.

• Synonyms:

  C-type lectin domain family 4 member C|Blood dendritic cell antigen 2 (BDCA-2)|C-type lectin superfamily member 7|Dendritic lectin|CLEC4C|BDCA2|CLECSF11|CLECSF7|DLEC|HECL

• Gene ID:

  170482

• UniProt:

  Q8WTT0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  C-type lectin domain family 4, member C

• Target:

  CLEC4C

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4