CKMT2 antibody

• Background :

  Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

• Synonyms :

  Creatine kinase S-type, mitochondrial|Basic-type mitochondrial creatine kinase (Mib-CK) |Sarcomeric mitochondrial creatine kinase (S-MtCK) |CKMT2

• Gene ID :

  1160

• UniProt :

  P17540

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Creatine kinase, mitochondrial 2 (sarcomeric)

• Target :

  CKMT2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Neuroscience, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  48 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC