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CKMT2 antibody

CAT: 0710-FNab01728Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01728Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
Synonyms
Creatine kinase S-type, mitochondrial|Basic-type mitochondrial creatine kinase (Mib-CK) |Sarcomeric mitochondrial creatine kinase (S-MtCK) |CKMT2
Gene ID
1160
UniProt
P17540
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Creatine kinase, mitochondrial 2 (sarcomeric)
Target
CKMT2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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