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CHTF18 antibody

CAT: 0710-FNab01701Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01701Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA) . The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.
Synonyms
Chromosome transmission fidelity protein 18 homolog (hCTF18) |CHL12|CHTF18|C16orf41|CTF18
Gene ID
63922
UniProt
Q8WVB6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
CTF18, chromosome transmission fidelity factor 18 homolog
Target
CHTF18
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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