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DDIT3 antibody

CAT: 0710-FNab01668Size: 100 µgDry Ice: NoHazardous: No
CAT#: FNab01668Size: 100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Synonyms
DNA damage-inducible transcript 3 protein (DDIT-3) |C/EBP zeta|C/EBP-homologous protein (CHOP) |C/EBP-homologous protein 10 (CHOP-10) |CCAAT/enhancer-binding protein homologous protein|Growth arrest and DNA damage-inducible protein GADD153|DDIT3|CHOP|CHOP10|GADD153
Gene ID
1649
UniProt
P35638
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
DNA-damage-inducible transcript 3
Target
DDIT3
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB
Field of Research
Epigenetics, Stem Cells, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
30 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5H7
Tested Applications
ELISA, WB
Immunogen Sequence
1-169aa

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