CHMP2B antibody

CAT: 0710-FNab01659Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab01659Size:100 µg
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Background
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Synonyms
Charged multivesicular body protein 2b|CHMP2.5|Chromatin-modifying protein 2b (CHMP2b) |Vacuolar protein sorting-associated protein 2-2 (Vps2-2, hVps2-2) |CHMP2B
Gene ID
25978
UniProt
Q9UQN3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Chromatin modifying protein 2B
Target
CHMP2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
28 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC

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