CD63 antibody

• Background :

  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

• Synonyms :

  CD63 antigen|Granulophysin|Lysosomal-associated membrane protein 3 (LAMP-3) |Lysosome integral membrane protein 1 (Limp1) |Melanoma-associated antigen ME491|OMA81H|Ocular melanoma-associated antigen|Tetraspanin-30 (Tspan-30) |CD63|MLA1|TSPAN30

• Gene ID :

  967

• UniProt :

  P08962

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  CD63 molecule

• Target :

  CD63

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, WB

• Field of Research :

  Cancer, Immunology, Cardiovascular, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  26-60 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, WB

• Immunogen Sequence :

  104-209aa