CCL17 antibody

• Background:

  This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

• Synonyms:

  C-C motif chemokine 17|CC chemokine TARC|Small-inducible cytokine A17|Thymus and activation-regulated chemokine|CCL17|SCYA17|TARC

• Gene ID:

  6361

• UniProt:

  Q92583

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  chemokine (C-C motif) ligand 17

• Target:

  CCL17

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, WB

• Field of Research:

  Immunology, Signal Transduction, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  12 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4