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BUB1 antibody

CAT: 0710-FNab00987Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00987Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Synonyms
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) |BUB1A|BUB1|BUB1L
Gene ID
699
UniProt
O43683
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Budding uninhibited by benzimidazoles 1 homolog (yeast)
Target
BUB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Cancer, Cell Division and Proliferation, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
133 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

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