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BMPR1A antibody

CAT: 0710-FNab00922Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00922Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Synonyms
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor, BMPR-1A) |Activin receptor-like kinase 3 (ALK-3) |Serine/threonine-protein kinase receptor R5 (SKR5) |BMPR1A|ACVRLK3|ALK3
Gene ID
657
UniProt
P36894
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Bone morphogenetic protein receptor, type IA
Target
BMPR1A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Stem Cells, Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP

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