BMPR1A antibody

• Background:

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

• Synonyms:

  Bone morphogenetic protein receptor type-1A (BMP type-1A receptor, BMPR-1A) |Activin receptor-like kinase 3 (ALK-3) |Serine/threonine-protein kinase receptor R5 (SKR5) |BMPR1A|ACVRLK3|ALK3

• Gene ID:

  657

• UniProt:

  P36894

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Bone morphogenetic protein receptor, type IA

• Target:

  BMPR1A

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF, IP

• Field of Research:

  Stem Cells, Immunology, Cardiovascular

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  60 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF, IP