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BMPR2 antibody

CAT: 0710-FNab00923Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00923Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Synonyms
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor, BMPR-2) |Bone morphogenetic protein receptor type II (BMP type II receptor, BMPR-II) |BMPR2|PPH1
Gene ID
659
UniProt
Q13873
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Bone morphogenetic protein receptor, type II (serine/threonine kinase)
Target
BMPR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa, 97 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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