BMPR2 antibody

• Background :

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

• Synonyms :

  Bone morphogenetic protein receptor type-2 (BMP type-2 receptor, BMPR-2) |Bone morphogenetic protein receptor type II (BMP type II receptor, BMPR-II) |BMPR2|PPH1

• Gene ID :

  659

• UniProt :

  Q13873

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Bone morphogenetic protein receptor, type II (serine/threonine kinase)

• Target :

  BMPR2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IP

• Field of Research :

  Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Stem Cells

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:500-1:1000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  120 kDa, 97 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IP