BDNF antibody

• Background:

  During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

• Synonyms:

  Brain-derived neurotrophic factor (BDNF) |Abrineurin|BDNF precursor form (ProBDNF) |BDNF

• Gene ID:

  627

• UniProt:

  P23560

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Brain-derived neurotrophic factor

• Target:

  BDNF

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC,IF

• Field of Research:

  Neuroscience, Signal Transduction, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  28-37 kDa, 14 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  19-247AA