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BAG1 antibody

CAT: 0710-FNab00786Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00786Size:100 µg
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Background
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti- apoptotic effects of BCL2 and represents a link between growth factor receptors and anti- apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Synonyms
BAG family molecular chaperone regulator 1 (BAG-1) |Bcl-2-associated athanogene 1|BAG1|HAP
Gene ID
573
UniProt
Q99933
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
BCL2-associated athanogene
Target
BAG1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · Q99933

BAG family molecular chaperone regulator 1

BAG1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99933
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BAG1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
BAG-1
EC number
—
Processing
—
Secondary accessions
O75315, Q14414, Q53H32, Q5VZE8, Q5VZE9, Q5VZF0, Q96TG2, Q9Y2V4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Apoptosis

Molecular function

Chaperone

Cellular component

CytoplasmNucleus

PTM

PhosphoproteinUbl conjugation

Domain

Repeat

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