BACE2 antibody

• Background:

  Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

• Synonyms:

  Beta-secretase 2|Aspartic-like protease 56 kDa|Aspartyl protease 1 (ASP1, Asp 1) |Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2) |Down region aspartic protease (DRAP) |Memapsin-1|Membrane-associated aspartic protease 1|Theta-secretase|BACE2|AEPLC|ALP56|ASP21

• Gene ID:

  25825

• UniProt:

  Q9Y5Z0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Beta-site APP-cleaving enzyme 2

• Target:

  BACE2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Neuroscience, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:1000; IHC: 1:50-1:500

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  60 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC