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BACE2 antibody

CAT: 0710-FNab00782Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00782Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
Synonyms
Beta-secretase 2|Aspartic-like protease 56 kDa|Aspartyl protease 1 (ASP1, Asp 1) |Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2) |Down region aspartic protease (DRAP) |Memapsin-1|Membrane-associated aspartic protease 1|Theta-secretase|BACE2|AEPLC|ALP56|ASP21
Gene ID
25825
UniProt
Q9Y5Z0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Beta-site APP-cleaving enzyme 2
Target
BACE2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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