ATP5F1C antibody

Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1) -containing the extramembraneous catalytic core, and F (0) -containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F (1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha (3) beta (3) . Rotation of the central stalk against the surrounding alpha (3) beta (3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

ATP synthase subunit gamma, mitochondrial|ATP synthase F1 subunit gamma|F-ATPase gamma subunit|ATP5F1C|ATP5C|ATP5C1|ATP5CL1

509

P36542

Human, Mouse, Rat

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

ATP5F1C

ELISA, WB, IHC

Metabolism

Immunogen affinity purified

WB: 1:500-1:2000; IHC: 1:100-1:500

≥95% as determined by SDS-PAGE

Liquid

35 kDa

4°C with ice bag

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

ELISA, WB, IHC