ATIC antibody

• Background :

  Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571) .

• Synonyms :

  Bifunctional purine biosynthesis protein ATIC|AICAR transformylase/inosine monophosphate cyclohydrolase (ATIC) |Bifunctional purine biosynthesis protein ATIC, N-terminally processed|ATIC|PURH

• Gene ID :

  471

• UniProt :

  P31939

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

• Target :

  ATIC

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF

• Field of Research :

  Neuroscience, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:200-1:1000; IF: 1:10-1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  65 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF