ATIC antibody

• Background:

  Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571) .

• Synonyms:

  Bifunctional purine biosynthesis protein ATIC|AICAR transformylase/inosine monophosphate cyclohydrolase (ATIC) |Bifunctional purine biosynthesis protein ATIC, N-terminally processed|ATIC|PURH

• Gene ID:

  471

• UniProt:

  P31939

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

• Target:

  ATIC

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Neuroscience, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  65 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF