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ATG4B antibody

CAT: 0710-FNab00674Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00674Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Synonyms
Cysteine protease ATG4B|AUT-like 1 cysteine endopeptidase|Autophagy-related cysteine endopeptidase 1 (Autophagin-1) |Autophagy-related protein 4 homolog B (HsAPG4B, hAPG4B) |ATG4B|APG4B|AUTL1|KIAA0943
Gene ID
23192
UniProt
Q9Y4P1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ATG4 autophagy related 4 homolog B
Target
ATG4B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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