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ARHGAP10 antibody

CAT: 0710-FNab00546Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab00546Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity) .
Synonyms
Rho GTPase-activating protein 10|GTPase regulator associated with focal adhesion kinase 2 (GRAF2) |Graf-related protein 2|Rho-type GTPase-activating protein 10|ARHGAP10|GRAF2
Gene ID
79658
UniProt
A1A4S6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Rho GTPase activating protein 10
Target
ARHGAP10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
89 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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